Antifungal Activity and Preliminary Phytochemical Studies of Leaf Extract of Solanum Nigrum Linn
نویسنده
چکیده
Solanum nigrum Linn. is extensively used in Indian traditional and folk medicines to cure various skin ailments. The present study aims to evaluate the possibility for the presence of novel bio-active compounds against fungal pathogens. To determine antifungal activity, aqueous and crude extracts from leaves of S. nigrum Linn. was used against A. niger, A. flavus, C. albicans by dry weight method. Extracts prepared using crude solvents exhibited higher antifungal activity as compared to their corresponding aqueous extracts. No good activity was observed in the aqueous extract. The pathogen inhibiting activity was found to be dose dependent. The preliminary phytochemical screening of the leaves revealed the presence of Alkaloids, Flavonols, Flavones, Flavanols, Saponins and Steroids.
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